New Aminoquinoline with Schistosomicidal Activity

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1967 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 216, pages 282-283 (issn: 0028-0836, eissn: 1476-4687,

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Authors: N W, Bristow; B, Lessel; H C, Richards; G A, Williams;

doi: 10.1038/216282a0

pmid: 4964494

New Aminoquinoline with Schistosomicidal Activity

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Abstract

DURING routine testing of compounds, we have discovered schistosomicidal activity in a series of 5-aminoquinolines. Many compounds with this general formula were made and tested and some were found to have activity, but one compound was outstanding. This was 6-chloro-5-β-diethylaminoethylamino-8-methylquinoline.

Related Organizations

University of Nottingham
United Kingdom
Pfizer (United States)
United States

Keywords

Mice, Dogs, Species Specificity, Cats, Quinolines, Animals, Schistosomiasis, Haplorhini, Rats

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