With reference to the depression research methods review of H. Tennen, J.A. Hall, and G. Affleck (1995) and the earlier recommendations of P. C. Kendall, S. D. Hollon, A. T. Beck, C. L. Hammen, and R. E. Ingram (1987), the present discussion considers and then reaffirms selected methods. Discussion includes issues such as the use of analogue vs. clinical samples, single vs. multiple assessments, self-report vs. structured diagnostic interviews, and the use of multiple gaiting and analyses of symptom clusters.