Toxicity of Carbon Dioxide: A Review
Copyright policy )Toxicity of Carbon Dioxide: A Review
The toxicity of carbon dioxide has been established for close to a century. A number of animal experiments have explored both acute and long-term toxicity with respect to the lungs, the cardiovascular system, and the bladder, showing inflammatory and possible carcinogenic effects. Carbon dioxide also induces multiple fetal malformations and probably reduces fertility in animals. The aim of the review is to recapitulate the physiological and metabolic mechanisms resulting from CO(2) inhalation. As smokers are exposed to a high level of carbon dioxide (13%) that is about 350 times the level in normal air, we propose the hypothesis that carbon dioxide plays a major role in the long term toxicity of tobacco smoke.
Central Nervous System, 570, MESH: Acidosis, MESH: Reproduction, MESH: Carbon Dioxide, Cardiovascular System, MESH: Carcinogens, Hypercapnia, MESH: Bicarbonates, MESH: Central Nervous System, Animals, Humans, MESH: Animals, MESH: Lung, Lung, [INFO.INFO-BI] Computer Science [cs]/Bioinformatics [q-bio.QM], MESH: Humans, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], MESH: Cardiovascular System, Reproduction, Carbon Dioxide, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], [SDV.TOX] Life Sciences [q-bio]/Toxicology, [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, Bicarbonates, MESH: Hypercapnia, [SDV.TOX]Life Sciences [q-bio]/Toxicology, Respiratory, Carcinogens, Acidosis, Respiratory, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
Central Nervous System, 570, MESH: Acidosis, MESH: Reproduction, MESH: Carbon Dioxide, Cardiovascular System, MESH: Carcinogens, Hypercapnia, MESH: Bicarbonates, MESH: Central Nervous System, Animals, Humans, MESH: Animals, MESH: Lung, Lung, [INFO.INFO-BI] Computer Science [cs]/Bioinformatics [q-bio.QM], MESH: Humans, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], MESH: Cardiovascular System, Reproduction, Carbon Dioxide, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], [SDV.TOX] Life Sciences [q-bio]/Toxicology, [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, Bicarbonates, MESH: Hypercapnia, [SDV.TOX]Life Sciences [q-bio]/Toxicology, Respiratory, Carcinogens, Acidosis, Respiratory, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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