Fluorination of Flavones and Chromones Using Elemental Fluorine

descriptionPublicationkeyboard_double_arrow_right Article 12 Jun 2014 English Publisher:American Chemical Society (ACS)Journal:The Journal of Organic Chemistry, volume 79, pages 7,261-7,265 (issn: 0022-3263, eissn: 1520-6904,

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Authors: Inna, Vints; Shlomo, Rozen;

doi: 10.1021/jo5009542

pmid: 24885634

Fluorination of Flavones and Chromones Using Elemental Fluorine

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Abstract

Flavonoids are abundant micronutrients in our diet, possessing various biological activities. Fluorine was successfully added across the double bond of various flavones and chromones. The difluoro derivative products were easily dehydrofluorinated to form the corresponding 3-fluoroflavones and 3-fluorochromones.

Related Organizations

Tel Aviv University
Israel

Keywords

Flavonoids, Biological Products, Magnetic Resonance Spectroscopy, Molecular Structure, Chromones, Fluorine, Flavones

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