We review the characteristics of nucleosynthesis in ‘hypernovae’, i.e., core-collapse supernovae with very large explosion energies (≳ 1052 ergs). The hypernova yields show the following characteristics: (i) the mass ratio between the complete and incomplete Si burning regions is larger in hypernovae than normal supernovae. As a result, higher energy explosions tend to produce larger [(Zn, Co, V)/Fe] and smaller [(Mn, Cr)/Fe], which could explain the trend observed in very metal-poor stars; (ii) because of enhanced α-rich freeze-out, 44Ca, 48Ti, and 64Zn are produced more abundantly than in normal supernovae. The large [(Ti, Zn)/Fe] ratios observed in very metal poor stars strongly suggest a significant contribution of hypernovae; and (iii) oxygen burning takes place in more extended regions in hypernovae to synthesize a larger amount of Si, S, Ar, and Ca (‘Si’), which makes the ‘Si’/O ratio larger. The abundance pattern of the starburst galaxy M 82 may be attributed to hypernova explosions. We thus suggest that hypernovae make important contribution to the early Galactic (and cosmic) chemical evolution.