In the 10 year period from May, 1973, to May, 1983, a total of 251 pneumonectomies were undertaken. Total unilateral bronchiectasis, the consequence of previous tuberculosis, occurred in 67.3% of cases and was the major indication for pneumonectomy. Of the 251 pneumonectomies, 14.7% were done through an empyema. The management of patients undergoing this procedure is discussed. There were two operative deaths among the 37 patients. Postpneumonectomy empyema developed in 16 patients (45.7%), and five of these patients required thoracoplasty, five left the hospital with an open drain or sinus, and in six the empyema was sterilized.