Abstract Turkey, one of the twenty largest economies in the world is currently undergoing dynamic economic growth. Rich deposits of metal ores, i.e. iron, chromium, copper, zinc and lead ores, extraction of crude oil, bituminous coal and chemical raw materials affect the country’s economic development and affect the functioning of the natural environment. The largest cities of Turkey, i.e. Istanbul, Ankara, Izmir, Bursa, Adana, etc. are not only the country’s economic hallmark, but also a source of high emissions from technical and communication infrastructure. The impact of transport emissions or industrial pollution affects the share of green space in cities and the health of residents in large cities. Actions of municipal authorities may contribute to reducing adverse factors in the environment, which will improve the quality of life along with ensuring simultaneous economic development. The article presents the problems of the largest cities in Turkey in managing urban logistic processes and their impact on the natural environment, together with the opportunities of eliminating unfavorable ecological factors while simultaneously maintaining economic growth.