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The human virome: new tools and concepts

Authors: Marc Eloit; Marc Eloit; Marc Lecuit;

The human virome: new tools and concepts

Abstract

The human virome is the viral component of the microbiome. Its composition, and interindividual and temporal variability are not precisely known. Its impact on human health has received less attention than that of the bacterial microbiome, but is likely to be equally important, both in homeostasis and disease. Here we review the recent advances in this field and the questions that arise in the context of our rapidly increasing knowledge regarding the composition and function of the human virome. With the ever-extending use of next-generation sequencing (NGS) on a variety of clinical samples, rapid progress on the composition of the human virome and its impact upon human health are to be expected in the coming years.

Keywords

Opinion, [SDV]Life Sciences [q-bio], T-RM CELLS, 610, HUMAN GYROVIRUS, microbiome, virus, SYMBIOTIC PROTECTION, MESH: Viruses, MESH: Sequence Analysis, HEPATITIS-E VIRUS, 616, MESH: Microbiota, Humans, HUMAN PAPILLOMAVIRUSES, MESH: High-Throughput Nucleotide Sequencing, virome, metagenomics, MESH: Humans, IDENTIFICATION, Microbiota, High-Throughput Nucleotide Sequencing, DNA, Sequence Analysis, DNA, [SDV] Life Sciences [q-bio], MESH: Virus Diseases, BACTERIAL-INFECTION, Virus Diseases, Viruses, next-generation sequencing, HERPESVIRUS LATENCY, HUMAN FECES, SKIN

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    106
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 1%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
106
Top 10%
Top 10%
Top 1%
Green
bronze