
In this paper, a semi-parametric generalization of the Cox model that permits crossing hazard curves is described. A theoretical framework for estimation in this model is developed based on penalized likelihood methods. It is shown that the optimal solution to the baseline hazard, baseline cumulative hazard and their ratio are hyperbolic splines with knots at the distinct failure times.
Censored data models, Estimation in survival analysis and censored data, crossing hazards, splines, proportional hazards, penalized likelihood, censored survival data analysis
Censored data models, Estimation in survival analysis and censored data, crossing hazards, splines, proportional hazards, penalized likelihood, censored survival data analysis
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