Abstract This paper focuses on developing a simulation model for the analysis of transmission pipeline network system (TPNS) with detailed characteristics of compressor stations. Compressor station is the key element in the TPNS since it provides energy to keep the gas moving. The simulation model is used to create a system that simulates TPNS with different configurations to get pressure and flow parameters. The mathematical formulations for the TPNS simulation were derived from the principles of flow of fluid through pipe, mass balance and compressor characteristics. In order to determine the unknown pressure and flow parameters, a visual C++ code was developed based on Newton–Raphson solution technique. Using the parameters obtained, the model evaluates the energy consumption for various configurations in order to guide for the selection of optimal TPNS. Results from the evaluations of the model with the existing TPNS and comparison with the existing approaches showed that the developed simulation model enabled to determine the operational parameters with less than 10 iterations. Hence, the simulation model could assist in decisions regarding the design and operations of the TPNS.