AbstractEach of industries including oil and gas industri should pay attention to aspects of industrial hygiene as well as possible given the magnitude of the risk level of activity contained in each employee. Industrial hygiene is the study of how to anticipate, recognize, evaluate, and control of workplace conditions that can lead to workers experiencing illness or injury. This oil and gas company as one of the oil and gas companies are faced with the problem of how to reduce the impact of occupational health. This study aims to design what should be done to manage occupational health risks in oil and gas company based on the framework of industrial hygiene.Data obtained from the Walk-through survey, Health Risk Assessent (HRA), and study the documents. This data is used as input to design the industrial hygiene work programs. The design of the work program was conducted with a variety of approaches, including strategic management concepts, isrs7, and the concept of industrial hygiene engineering, such as Occupational Safety & Health Administration (OSHA) and National Institute of Occupational Safety & Health (NIOSH) framework. This design gave birth to 34 strategic objectives, 113 Key Performance Indicator, and 18 major work program. Management Commitment, Employee Involvement, Written Program, Documentation and Reporting System, Contractor Management, Periodic Inspections, Hazard Information Collecting, Hazard Analyses, Hazard Control, Assessment Maintenance Equipments, Machine Tools and Maintenance, Emergency Preparedness and Response, Training, Medical Management, Audit, Compliance of Regulations and Standards, Trend Analyses and Program Effectiveness, and Final Review are the major work program.Three of the eighteen-work program, the Hazard Information Collecting, Hazard Analyses and Hazard Control, will be further differentiated by the type of hazard. Three work program is a program of work that focus directly to the handling of risk.