Toxoplasma Retromer Is Here to Stay

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2016 English Publisher:Elsevier BVJournal:Trends in Parasitology, volume 32, pages 758-760 (issn: 1471-4922,

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Authors: Olivia L, McGovern; Vern B, Carruthers;

doi: 10.1016/j.pt.2016.05.007

pmid: 27247246

pmc: PMC5048501

Toxoplasma Retromer Is Here to Stay

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Abstract

How the protozoan pathogen Toxoplasma gondii and related parasites shuttle proteins through their intricate system of endomembranous compartments remains unclear. Sangaré et al. show that the Toxoplasma retromer complex is essential for parasite viability through its role in protein targeting to multiple locales and its interactions with newly identified partners.

Related Organizations

University of Michigan–Flint
United States
University of Michigan–Ann Arbor
United States

Keywords

Organelles, Protein Transport, rab GTP-Binding Proteins, Multiprotein Complexes, Protozoan Proteins, Animals, Toxoplasma, Host-Parasite Interactions, rab11 GTP-Binding Proteins

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