We use a recently developed model of relativistic meson-exchange currents to compute the neutron-proton and proton-proton yields in $(��_��,��^-)$ scattering from $^{12}$C in the 2p-2h channel. We compute the response functions and cross sections with the relativistic Fermi gas model for different kinematics from intermediate to high momentum transfers. We find a large contribution of neutron-proton configurations in the initial state, as compared to proton-proton pairs. In the case of charge-changing neutrino scattering the 2p-2h cross section of proton-proton emission ({\it i.e.,} np in the initial state) is much larger than for neutron-proton emission ({\it i.e.,} two neutrons in the initial state) by a $(��,q)$-dependent factor. The different emission probabilities of distinct species of nucleon pairs are produced in our model only by meson-exchange currents, mainly by the $��$ isobar current. We also analyze other effects including exchange contributions and the effect of the axial and vector currents.

9 pages and 8 figures