This study explored the feasibility and acceptability of using Motivational Interviewing (MI) in the home setting with families of preschoolers.Using mixed-methods pilot data from an MI-based obesity prevention intervention delivered via home visits by health educators (HEs) with 44 families (n = 17 four home visit group; n = 14 two home visit group), we examined: 1) fidelity of MI adherence by HEs; 2) parents' perceptions of the intervention; and 3) HEs insights pertaining to the intervention's delivery.Multiple measures of MI fidelity were deemed to exceed defined proficiency levels. Ninety-three percent of families reported being "satisfied" to "very satisfied" with the intervention. HEs reported building a high level of trust with families and gaining a thorough understanding of familial context. Parents appreciated how HEs' were knowledgeable and provided personalized attention when discussing health goals. Some parents suggested more directive advice and follow-up visits as ways to improve the intervention.Home-based MI was conducted with a high level of fidelity, was well accepted by families and practitioners.Our findings from parents and MI practitioners provide key learnings that can inform future behavior change interventions that propose to use MI within the home setting.