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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Otolaryngologyarrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Otolaryngology
Article . 2007 . Peer-reviewed
License: Wiley Online Library User Agreement
Data sources: Crossref
Otolaryngology
Article . 2007
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Bisphosphonates and jaw osteonecrosis: The UAMS experience

Authors: Brett M, Clarke; Jennings, Boyette; Emre, Vural; James Y, Suen; Elias J, Anaissie; Brendan C, Stack;

Bisphosphonates and jaw osteonecrosis: The UAMS experience

Abstract

BackgroundOver the past year at least 10 case series and several case reports on osteonecrosis of the jaw (ONJ) have been published with most found in the oral surgery literature. This clinical entity is largely unknown to head and neck surgeons.MethodsRetrospective chart review.ResultsA total of 479 charts were reviewed, identifying 25 individuals meeting inclusion criteria. Mean age was 63.4 (standard deviation, 9.9) years; 40% were female. Multiple myeloma was the most common comorbidity. Twenty‐five patients were treated with bisphosphonates for 4.4 years (range, 1 to 8 years); most commonly pamidronate before ONJ diagnosis. Forty‐two percent (10) took steroids within the month before diagnosis. Fifty‐two percent (11) underwent dental work before developing ONJ.ConclusionThese data reflect the importance of awareness of the possibility of ONJ with bisphosphonate therapy.

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Keywords

Male, Hyperbaric Oxygenation, Time Factors, Bone Density Conservation Agents, Diphosphonates, Imidazoles, Osteonecrosis, Pamidronate, Middle Aged, Zoledronic Acid, Anti-Bacterial Agents, Curettage, Treatment Outcome, Adrenal Cortex Hormones, Humans, Female, Dental Care, Multiple Myeloma, Jaw Diseases, Retrospective Studies

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
45
Top 10%
Top 10%
Top 10%
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