Glia, Adenosine, and Sleep

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2009 English Publisher:Elsevier BVJournal:Neuron, volume 61, pages 156-157 (issn: 0896-6273,

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Authors: Jones, Barbara E.;

doi: 10.1016/j.neuron.2009.01.005

pmid: 19186158

Glia, Adenosine, and Sleep

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Abstract

Sleep is regulated by a homeostatic process that has long been thought to involve adenosine (AD) originating from neurons. In this issue of Neuron, Halassa et al. present evidence that sleep homeostasis depends upon gliotransmission and associated accumulation of AD that dampens neuronal excitability.

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Keywords

Neurons, Adenosine, Neuroscience(all), Receptors, Purinergic P1, Brain, Cell Communication, Adenosine Triphosphate, Animals, Homeostasis, Humans, Sleep, Neuroglia

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