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Jagiellonian University Repository
Article . 2006
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Neurochemistry International
Article . 2006 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
Neurochemistry International
Article . 2006
Data sources: Europe PubMed Central
https://dx.doi.org/10.1016/j.n...
Article
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Rat brain proteome in morphine dependence

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2006 Poland English Publisher:Elsevier BVJournal:Neurochemistry International, volume 49, pages 401-406 (issn: 0197-0186, Copyright policy )
Authors: Bierczyńska-Krzysik, Anna; Bonar, Emilia; Drabik, Anna; Noga, Marek; Suder, Piotr; Dylag, Tomasz; Dubin, Adam; +2 Authors

doi: 10.1016/j.neuint.2006.01.024

pmid: 16581157

Rat brain proteome in morphine dependence

Abstract

The aim of this study was to reveal potential markers associated with drug dependence, using the proteomic approach. Gels containing samples derived from morphine-treated and control animals were compared and analyzed. Inspection of protein profiles, following TCA/acetone precipitation and the use of nano-scale liquid chromatography coupled to tandem mass spectrometry, allowed for identification of eleven potential dependence markers, mainly cytoplasmic and mitochondrial enzymes, e.g. proteins that belong to GTPase and GST superfamilies, ATPase, asparaginase or proteasome subunit p27 families.

Country
Poland
Related Organizations
Keywords

Brain Chemistry, Male, Proteome, proteome, Down-Regulation, protein profiling, Mass Spectrometry, Rats, morphine dependence, rat brain, Animals, Nanotechnology, Electrophoresis, Gel, Two-Dimensional, Electrophoresis, Polyacrylamide Gel, Rats, Wistar, Morphine Dependence, mass spectrometry

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    popularity
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
39
Average
Top 10%
Top 10%
Green
Related to Research communities
Neuroscience