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Molecular Cell
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Molecular Cell
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Molecular Cell
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GTP: Gatekeeper for Autophagy

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2010Publisher:Elsevier BVJournal:Molecular Cell, volume 39, pages 485-486 (issn: 1097-2765, Copyright policy )
Authors: Isabelle Beau; Patrice Codogno;

doi: 10.1016/j.molcel.2010.08.005

pmid: 20797620

GTP: Gatekeeper for Autophagy

Abstract

Chaperone-mediated autophagy (CMA) is involved in cellular quality control, and in the response to stress, deterioration in CMA contributes to the aging phenotype and to various disorders. The paper by Bandyopadhyay et al. in this issue of Molecular Cell demonstrates the role of GTP binding by elongation factor 1 alpha (EF1alpha) in regulating the lysosomal uptake of CMA substrates.

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Keywords

Cell Biology, Molecular Biology

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    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Average
Average
hybrid