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Journal of the Chinese Medical Association
Article . 2016 . Peer-reviewed
License: CC BY NC ND
Data sources: Crossref
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Journal of the Chinese Medical Association
Article
License: CC BY NC ND
Data sources: UnpayWall
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Is there an association between the Expanded Disability Status Scale and inflammatory markers in multiple sclerosis?

Authors: Guzel, Isil; Mungan, Semra; Oztekin, Zeynep Neşe; Ak, Fikri;

Is there an association between the Expanded Disability Status Scale and inflammatory markers in multiple sclerosis?

Abstract

Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease characterized by inflammation of white matter in the central nervous system. It has been indicated that this inflammation causes increased levels of proinflammatory cytokines. Therefore, we aimed to evaluate if there is a possible association between inflammatory markers and the Expanded Disability Status Scale (EDSS) score in patients with MS.We reviewed the data of 127 patients (91 women and 36 men) who were retrospectively diagnosed as MS according to the revised Mc Donald's criteria who were seen at our facility between January 2007 and December 2012. Patients were divided into two groups according to EDSS score: Group 1, EDSS 5. Additionally, NLR and CRP levels may be discriminative factors of adverse clinical outcomes.

Keywords

Medicine(all), Adult, Male, Multiple Sclerosis, Neutrophils, expanded disability status scale, Middle Aged, multiple sclerosis, Severity of Illness Index, C-Reactive Protein, inflammation, Humans, Female, Lymphocytes, Retrospective Studies

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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    51
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
51
Top 10%
Top 10%
Top 10%
gold