The advent of the Fourth Industrial Revolution is expected to deeply change several aspects of the manufacturing industry. Among them, the logistics and supply chain activities will be affected by these changes both at operational and managerial level to face the market drivers of flexibility and mass-customisation. In this context, the work of operators in internal and external logistics will be affected by these changes and increase the interaction between humans and machines. The evolution of the roles of humans in Logistics 4.0 will give birth to "The Logistics Operator 4.0"paradigm. The aim of this paper is to investigate the impacts of Industry 4.0 technologies on the different roles of logistics operators that work in the main logistics domains and areas.