Abstract The passage of Jupiter and Saturn through mutual 1:2 mean-motion resonance has recently been put forward as explanation for their relatively high eccentricities [Tsiganis, K., Gomes, R., Morbidelli, A., Levison, H.F., 2005. Nature 435, 459–461] and the origin of Jupiter's Trojans [Morbidelli, A., Levison, H.F., Tsiganis, K., Gomes, R., 2005. Nature 435, 462–465]. Additional constraints on this event based on other small-body populations would be highly desirable. Since some outer satellite orbits are known to be strongly affected by the near-resonance of Jupiter and Saturn (“the Great Inequality”; Cuk, M., Burns, J.A., 2004b. Astron. J. 128, 2518–2541), the irregular satellites are natural candidates for such a connection. In order to explore this scenario, we have integrated 9200 test particles around both Jupiter and Saturn while they went through a resonance-crossing event similar to that described by Tsiganis et al. [Tsiganis, K., Gomes, R., Morbidelli, A., Levison, H.F., 2005. Nature 435, 459–461]. The test particles were positioned on a grid in semimajor axes and inclinations, while their initial pericenters were put at just 0.01 AU from their parent planets. The goal of the experiment was to find out if short-lived bodies, spiraling into the planet due to gas drag (or alternatively on orbits crossing those of the regular satellites), could have their pericenters raised by the resonant perturbations. We found that about 3% of the particles had their pericenters raised above 0.03 AU (i.e. beyond Iapetus) at Saturn, but the same happened for only 0.1% of the particles at Jupiter. The distribution of surviving particles at Saturn has strong similarities to that of the known irregular satellites. If saturnian irregular satellites had their origin during the 1:2 resonance crossing, they present an excellent probe into the early Solar System's evolution. We also explore the applicability of this mechanism for Uranus, and find that only some of the uranian irregular satellites have orbits consistent with resonant pericenter lifting. In particular, the more distant and eccentric satellites like Sycorax could be stabilized by this process, while closer-in moons with lower eccentricity orbits like Caliban probably did not evolve by this process alone.