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Sex determination and sex reversal

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2006 Italy Publisher:Elsevier BVJournal:Current Opinion in Genetics & Development, volume 16, pages 289-292 (issn: 0959-437X,

Authors: G. Camerino; P. Parma; O. Radi; S. Valentini;

doi: 10.1016/j.gde.2006.04.014

pmid: 16647843

handle: 2434/24047 , 11571/136806

Sex determination and sex reversal

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Abstract

Sex determination in mammals is based on a genetic cascade that controls the fate of the gonads. Gonads will then direct the establishment of phenotypic sex through the production of hormones. Different types of sex reversal are expected to occur if mutations disrupt one of the three steps of gonadal differentiation: formation of the gonadal primordia, sex determination, and testis or ovary development.

Country

Italy

Related Organizations

Keywords

sex reversal, Sex Chromosomes, disorders of sex development, sex determination, Disorders of Sex Development, Cell Differentiation, Sex Determination Processes, 576, 616, Animals, Humans, Gonads

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	37
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%