Many Transmission Power Control (TPC) algorithms have been proposed in the past, yet the conditions under which they are evaluated do not always reflect typical Internet-of-Things (IoT) scenarios. IoT networks consist of several source nodes transmitting data simultaneously, possibly along multiple hops. Link failures are highly frequent, causing the TPC algorithm to kick-in quite often. To this end, in this paper we study the impact that frequent TPC actions have across different layers. Our study shows how one node’s decision to scale its transmission power can affect the performance of both routing and MAC layers of multiple other nodes in the network, generating cascading packet retransmissions and forcing far too many nodes to consume more energy. We find that crucial objectives of TPC such as conserving energy and increasing network capacity are severely undermined in multi-hop networks.