
Insulin-like growth factor 1 (IGF-1) is a pleiotropic polypeptide. Its expression is tightly regulated and it plays significant roles during early development, maturation, and adulthood. This article discusses the roles of IGF-1 in determination of body size, skeletal acquisition, muscle growth, carbohydrate metabolism, and longevity, as learned from mouse models.
Male, Reproduction, Longevity, Lipid Metabolism, Mice, Insulin-Like Growth Factor II, Models, Animal, Animals, Body Size, Humans, Female, Insulin-Like Growth Factor I, Muscle, Skeletal, Signal Transduction
Male, Reproduction, Longevity, Lipid Metabolism, Mice, Insulin-Like Growth Factor II, Models, Animal, Animals, Body Size, Humans, Female, Insulin-Like Growth Factor I, Muscle, Skeletal, Signal Transduction
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