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Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2017 English Publisher:Elsevier BVJournal:Data in Brief, volume 13, pages 53-59 (issn: 2352-3409, Copyright policy )
Authors: J. Kosman; A. Stanislawska; A. Gluszynska; B. Juskowiak;

doi: 10.1016/j.dib.2017.05.020

pmid: 28560283

pmc: PMC5443925

Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate

Abstract

In this article newly synthesized azide derivative of hemin and DNA-hemin conjugate are characterized. Hemin-azide was purified using HPLC and characterized using elemental analysis, IR and NMR. The DNA-hemin conjugate was obtained via click chemistry [1] and click reaction was carried out using traditional Cu-catalyzed and Cu-free approaches. The final product was successfully obtained using Cu-free cycloaddition. The identity of product was confirmed using Maldi TOF spectrometry. Obtained hemin-DNA conjugate exhibited peroxidase-like activity.

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Keywords

Q1-390, Science (General), Computer applications to medicine. Medical informatics, R858-859.7, Data Article

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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
Green
gold