Rapping about Mechanotransduction

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2018 English Publisher:Elsevier BVJournal:Developmental Cell, volume 46, pages 678-679 (issn: 1534-5807,

Copyright policy )

Authors: Consuelo, Ibar; Kenneth D, Irvine;

doi: 10.1016/j.devcel.2018.09.007

pmid: 30253168

Rapping about Mechanotransduction

- Summary
- Subjects
- Metrics

Abstract

Mechanical cues can regulate cell proliferation and differentiation through the Hippo-YAP signaling network. Reporting in Nature, Meng et al. (2018) show that the Ras-related GTPase RAP2 connects extracellular matrix stiffness to Hippo pathway regulation, adding to our understanding of how mechanical cues are converted into changes in YAP activity.

Related Organizations

Rutgers, The State University of New Jersey
United States

Keywords

Phosphoproteins, Mechanotransduction, Cellular, Adaptor Proteins, Signal Transducing, Cell Proliferation, Extracellular Matrix, Signal Transduction

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	7
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%