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Developmental Cell
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Developmental Cell
Article . 2017 . Peer-reviewed
License: Elsevier Non-Commercial
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Article . 2017
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Article . 2017
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Pushing Yap into the Nucleus with Shear Force

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2017 English Publisher:Elsevier BVJournal:Developmental Cell, volume 40, pages 517-518 (issn: 1534-5807, Copyright policy )
Authors: Lai, J.; Stainier, D.;

doi: 10.1016/j.devcel.2017.03.008

pmid: 28350983

handle: 21.11116/0000-0004-51D2-3

Pushing Yap into the Nucleus with Shear Force

Abstract

Endothelial cells line blood vessels and experience shear stress from blood flow. In this issue of Developmental Cell, Nakajima and colleagues (2017) show that in zebrafish Yap responds to blood flow by translocating into the nucleus, where it drives a genetic program to maintain vascular stability.

Related Organizations
Keywords

Cell Nucleus, Animals, Endothelial Cells, Endothelium, Stress, Mechanical, Zebrafish

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 13
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
13
Top 10%
Average
Top 10%
hybrid