Candidate and non-candidate genes in behavior genetics
Copyright policy )Candidate and non-candidate genes in behavior genetics
In this review we discuss recent developments in psychiatric genetics: on the one hand, studies using whole genome approaches (genome-wide association studies (GWAS) and exome sequencing) are coming close to finding genes and molecular variants that contribute to disease susceptibility; on the other candidate genes, such as the serotonin transporter, continue to dominate in genetic studies of brain imaging phenotypes and in protracted searches for gene by environment interactions. These two areas intersect, in that new information about genetic effects from whole genome approaches, should (but does not always) inform the single locus analyses.
- Wellcome Trust United Kingdom
- University of Oxford United Kingdom
- University of Bristol (UoB) United Kingdom
- University of Bristol United Kingdom
- Wellcome Centre for Human Genetics United Kingdom
Behavior, name=Brain and Behaviour, Neuroscience(all), Mental Disorders, 610, /dk/atira/pure/core/keywords/brain_and_behaviour, Article, Humans, /dk/atira/pure/core/keywords/tobacco_and_alcohol, Genetic Predisposition to Disease, name=Tobacco and Alcohol, Genome-Wide Association Study
Behavior, name=Brain and Behaviour, Neuroscience(all), Mental Disorders, 610, /dk/atira/pure/core/keywords/brain_and_behaviour, Article, Humans, /dk/atira/pure/core/keywords/tobacco_and_alcohol, Genetic Predisposition to Disease, name=Tobacco and Alcohol, Genome-Wide Association Study
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