This study evaluates the impact of using the software program AudioMetro, a tool that supports the orientation and mobility of people who are blind in the Metro system of Santiago de Chile. A quasi-experimental study considering experimental and control groups and using the paired Student's t in a two sample test analysis (pretest-posttest) was carried out to measure the learner's performance and progress in the navigation through the Metro. Participants completed a number of cognitive tasks related to their navigation through the metro system using the tool designed. Results indicate that AudioMetro could be an adequate and complementary tool for the development of cognitive and sensory skills, which are fundamental axes for orientation and mobility.