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BMI and hyperinsulinemia in children

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2009Publisher:Elsevier BVJournal:Clinical Biochemistry, volume 42, pages 1,427-1,430 (issn: 0009-9120,

Authors: Michael Lehrke; Peter Schwandt; Peter Schwandt; Uli C. Broedl; Michael Vogeser; Klaus G. Parhofer; Gerda-Maria Haas;

doi: 10.1016/j.clinbiochem.2009.06.011

pmid: 19560447

BMI and hyperinsulinemia in children

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Abstract

Overweight is associated with hyperinsulinemia in adults and children. The aim of our study was to test if body mass index (BMI) alone or in combination with waist circumference (WC) predicts hyperinsulinemia in individual children.In 466 healthy German schoolchildren aged 7 to 12 years enrolled in the population based PEP Family Heart Study, anthropometric data, standard laboratory data and fasting serum insulin concentrations were assessed.Among children with hyperinsulinemia (fasting serum insulin concentrations>85th age specific percentile), 56% were not overweight (BMI-for-age85th percentile) was not a better predictor of hyperinsulinemia, neither alone nor in combination with BMI.Overweight and abdominal obesity are poor indicators of hyperinsulinemia in individual German school children aged 7 to 12 years. Insulin measurement seems to be necessary to reliably detect hyperinsulinemia.

Related Organizations

Ludwig-Maximilians-Universität München
Germany
Prevention Institute
United States

Keywords

Blood Glucose, Male, Biometry, Cholesterol, HDL, Abdominal Fat, Blood Pressure, Cholesterol, LDL, Fasting, Overweight, Body Mass Index, Cholesterol, Predictive Value of Tests, Germany, Hyperinsulinism, Humans, Insulin, Female, Obesity, Child, Triglycerides

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