Cell-free Screening for NOX Inhibitors

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2012 Switzerland English Publisher:Elsevier BVJournal:Chemistry & Biology, volume 19, pages 664-665 (issn: 1074-5521,

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Authors: Bedard, Karen; Jaquet, Vincent;

doi: 10.1016/j.chembiol.2012.06.002

pmid: 22726678

Cell-free Screening for NOX Inhibitors

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Abstract

NOX enzymes are major ROS generators in pathological states and represent a promising pharmacological target. In this issue of Chemistry & Biology, Smith and colleagues developed an original and elegant cell-free assay to identify specific Nox2 inhibitors in a high throughput manner.

Country

Switzerland

Related Organizations

University of Geneva
Switzerland
University Hospital of Geneva
Switzerland
Dalhousie University
Canada
Geneva College
United States

Keywords

Pharmacology, Clinical Biochemistry, Drug Discovery, Molecular Medicine, 616.07, Biochemistry, Molecular Biology

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