Bacteriophage Prevents Alcoholic Liver Disease

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2020 Switzerland English Publisher:Elsevier BVJournal:Cell, volume 180, pages 218-220 (issn: 0092-8674,

Copyright policy )Funded by:EC | Healthybiota

Authors: Colakoglu, Melis; Xue, Jing; Trajkovski, Mirko;

doi: 10.1016/j.cell.2019.12.034

pmid: 31978341

Bacteriophage Prevents Alcoholic Liver Disease

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Abstract

Alcoholic hepatitis is a severe alcohol-associated liver disease with minimal treatment options. A recent study by Duan et al. uncovers that the exotoxin-secreting gut bacterium Enterococcus faecalis is a critical contributor to alcoholic hepatitis. This bacterium can now be eliminated with a bacteriophage, suggesting a new way to treat this life-threatening disease.

Country

Switzerland

Related Organizations

University of Geneva
Switzerland

Keywords

Hepatitis, Alcoholic, Enterococcus faecalis, Humans, Bacteriophages, 612, Liver Diseases, Alcoholic, Gastrointestinal Microbiome, ddc: ddc:612

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