A Slow Dance for Microtubule Acetylation

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2014 English Publisher:Elsevier BVJournal:Cell, volume 157, pages 1,255-1,256 (issn: 0092-8674,

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Authors: Kull, F. Jon; Sloboda, Roger D.;

doi: 10.1016/j.cell.2014.05.021

pmid: 24906144

A Slow Dance for Microtubule Acetylation

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Abstract

Microtubules contribute to diverse cellular processes through balancing dynamic, short-lived and stable, long-lived populations. One way in which long-lived microtubules are marked is by posttranslational acetylation of α-tubulin by tubulin acetyltransferase (TAT). Szyk et al. now provide insight into TAT's mechanism of action and its unique time-stamping ability.

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Keywords

Biochemistry, Genetics and Molecular Biology(all), Acetyltransferases, Humans, Microtubules

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