SnapShot: Cancer Vaccines

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2014 United States English Publisher:Elsevier BVJournal:Cell, volume 157, pages 516-5,160 (issn: 0092-8674,

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Authors: Palucka, Karolina; Banchereau, Jacques;

doi: 10.1016/j.cell.2014.03.044

pmid: 24725415

SnapShot: Cancer Vaccines

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Abstract

This SnapShot illustrates the main concepts and underlying biology of therapeutic vaccination in cancer. Dendritic cells (DCs) are an essential component of vaccination through their capacity to capture, process, and present antigens to T cells. We have come a long way in our understanding of what is needed to elicit therapeutic immunity when cancer escapes the natural barrier of protective immunity. This progress enables the development of novel vaccines.

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United States

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Keywords

570, Antigen Presentation, Biochemistry, Genetics and Molecular Biology(all), Life Sciences, Dendritic Cells, Cancer Vaccines, 510, Neoplasms, Medicine and Health Sciences, Animals, Humans

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