Sugarcoating ER Stress
Copyright policy )Sugarcoating ER Stress
The hexosamine biosynthetic pathway (HBP) generates metabolites for protein N- and O-glycosylation. Wang et al. and Denzel et al. report a hitherto unknown link between the HBP and stress in the endoplasmic reticulum. These studies establish the HBP as a critical component of the cellular machinery of protein homeostasis.
- Max Planck Society Germany
- Max Planck Institute of Biochemistry Germany
Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing), Male, Biochemistry, Genetics and Molecular Biology(all), Longevity, Proteins, Hexosamines, Regulatory Factor X Transcription Factors, Biosynthetic Pathways, DNA-Binding Proteins, Unfolded Protein Response, Animals, Humans, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Transcription Factors
Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing), Male, Biochemistry, Genetics and Molecular Biology(all), Longevity, Proteins, Hexosamines, Regulatory Factor X Transcription Factors, Biosynthetic Pathways, DNA-Binding Proteins, Unfolded Protein Response, Animals, Humans, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Transcription Factors
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