<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

Brain-derived neurotrophic factor, stress and depression: A minireview

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2009 Turkey Publisher:Elsevier BVJournal:Brain Research Bulletin, volume 78, pages 267-269 (issn: 0361-9230,

Authors: Kilic, Ertugrul; Ozan, Erol; GÖNÜL, ALİ SAFFET; Yulug, Burak;

doi: 10.1016/j.brainresbull.2008.12.002

pmid: 19111910

Brain-derived neurotrophic factor, stress and depression: A minireview

- Summary
- Subjects
- Metrics

Abstract

Brain-derived neurotrophic factor (BDNF) is a member of the nerve growth factor family, and is widely expressed in the adult mammalian brain. Besides its well known neuroprotective activity after traumatic brain injury the evidences regarding its activity dependent release by the pathophysiology of major depression are rapidly replicating. Considering the data that stress plays an important role by the development of depression which is characterized with prominent hippocampal cell death, as well as the well known neuroprotective effects of BDNF, we aimed to investigate the link between the BDNF, stress and depression. Thus we prepared a minireview in order to evaluate the neuroprotective role of BDNF by psychiatric disorders which are characterized with prominent neuronal cell death.

Country

Turkey

Related Organizations

Keywords

Neurons, Depressive Disorder, Major, Neuroprotective Agents, Cell Death, Stress, Physiological, Brain-Derived Neurotrophic Factor, Animals, Humans, Genetic Predisposition to Disease

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	79
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%