Copeptin: Pathophysiology and potential clinical impact

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2015 Poland English Publisher:Elsevier BVJournal:Advances in Medical Sciences, volume 60, pages 335-341 (issn: 1896-1126,

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Authors: Ewelina, Łukaszyk; Jolanta, Małyszko;

doi: 10.1016/j.advms.2015.07.002

pmid: 26233637

Copeptin: Pathophysiology and potential clinical impact

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Abstract

Copeptin, a C-terminal part of the precursor pre-provasopressin is a novel biomarker of arginine-vasopressin (AVP) system. Measurements of AVP concentration are not used in clinical practice because of technical difficulties. Copeptin is synthesized in stoichiometric ratio with AVP, hence it reflects vasopressin concentration in human plasma and serum. This review outlines current research concerning the role of copeptin as a prognostic marker in different diseases and its potential clinical value.

Country

Poland

Related Organizations

Wrocław Medical University
Poland
Medical University of Białystok
Poland

Keywords

Heart Failure, chronic - metabolism, Glycopeptides, Arginine vasopressin - metabolism, Arginine Vasopressin, Heart failure - metabolism, Biomarkers - metabolism, Animals, Humans, Glycopeptides - metabolism, Renal insufficiency, Renal Insufficiency, Chronic, Biomarkers

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