Publisher Summary This chapter discusses the clinical aspects of entrapment neuropathy. Nerve roots and peripheral nerves may become damaged by compressive physical forces. Compressive physical forces act on the nerves for periods of time varying from a few minutes to several years. The resulting clinical syndromes may be grouped according to the duration of compression. Acute compression occurs when a normal recumbent bodily posture is held for too long so that a nerve may be compressed by a hard object or the pressure of another limb, for example when resting on the elbows, sitting on a chair, crossing the legs, or sleeping. Pain and paraesthesia, numbness, and muscular weakness are experienced for a few minutes only, provided that the position is shifted. When adjacent anatomical structures impinge on the nerve trunks at the sites of entrapment, chronic compression of the nerves occurs. The development of clinical symptoms and signs (entrapment neuropathy) depends on the nature of the anatomical structures and the severity of pathological changes in the nerves themselves.