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Comparison of hepatitis B surface antigen and e antigen in predicting liver histology in hepatitis B e antigen-positive chronic hepatitis B patients

descriptionPublicationkeyboard_double_arrow_right Article 23 Jan 2014 English Publisher:Springer Science and Business Media LLCJournal:Hepatology International, volume 8, pages 216-223 (issn: 1936-0533, eissn: 1936-0541,

Authors: Mei Juan Cheng; Guo Qin Ruo; Hong Wang; Yin Zhou; Ming Shan Wang; Rong Yan;

doi: 10.1007/s12072-013-9502-8

pmid: 26202502

Comparison of hepatitis B surface antigen and e antigen in predicting liver histology in hepatitis B e antigen-positive chronic hepatitis B patients

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Abstract

The purpose of this study was to determine the relationship between hepatitis B e antigen (HBeAg) and hepatitis B surface antigen (HBsAg) levels and liver histology in HBeAg-positive patients with chronic hepatitis B virus (CHB) infection.Serum HBsAg and HBeAg levels were analyzed, and liver biopsies were obtained from 203 HBeAg-positive CHB patients (62.6 % males; median age 31.3 years). The upper limit of normal (ULN) for ALT in this study was 30 and 19 U/L for males and females, respectively. Histologic assessment was based on Scheuer classification.ALT <2 × ULN, fibrosis stage

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Zhejiang Provincial People's Hospital
China (People's Republic of)

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