Associations of GHSR gene polymorphisms with chicken growth and carcass traits
Copyright policy )Associations of GHSR gene polymorphisms with chicken growth and carcass traits
Ghrelin receptor (GHSR), or growth hormone secretagogue receptor, modulates many physiological effects by binding to its ligand and therefore is a candidate gene for chicken production performance. In this study, five polymorphisms (four SNP and a 'GGTACA' indel) of GHSR gene were genotyped in a F(2) full sib chicken population to investigate their associations with production traits. Results showed that c.739 + 726T > C (M2) was significantly associated with body weight (BW) at 28 days (BW28), BW90, dressed weight, eviscerated weight, eviscerated weight with giblet, breast muscle weight and leg muscle weight (P A (M1), c.3211-196_3211-181delGGTACA (M3), c.3211 + 75C > T (M4), and c.3211 + 150C > T (M5) with any growth and carcass traits was found. Haplotypes based on five polymorphisms were significantly associated with hatch weight, BW7, BW14, BW21 and breast angle (P < 0.05), as well as BW28 (P < 0.01). Therefore, it was concluded that M2 of the GHSR gene and the analyzed haplotypes were associated with some chicken growth and carcass traits.
- South China Agricultural University China (People's Republic of)
- University of Jinan China (People's Republic of)
- ShenZhen People’s Hospital China (People's Republic of)
Male, Genome, Meat, Polymorphism, Single Nucleotide, Quantitative Trait, Heritable, Gene Frequency, Haplotypes, Animals, Female, Receptors, Ghrelin, Chickens, Crosses, Genetic
Male, Genome, Meat, Polymorphism, Single Nucleotide, Quantitative Trait, Heritable, Gene Frequency, Haplotypes, Animals, Female, Receptors, Ghrelin, Chickens, Crosses, Genetic
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