Long- and short-term climatic curves were preliminarily established based on the comprehensive analysis of geochemical information since the Late Cenozoic in the Qinghai-Xizang (Qinghai-Tibet) Plateau. The curves show that the climate in the plateau was alternatively dry-warm and cold-wet during the period of 30-3.4 Ma when the plateau was not uplifted to an enough altitude and the monsoon was not completely formed either. In the period of 3.4-0.73 Ma, the climate fluctuated between dry-cold and wet-warm when the plateau was rapidly uplifted and the Asian monsoon was consequently formed. Since 0.73 Ma, the climate became even drier when the plateau continuously rose. In the Holocene period, the climate alternatively changed with a complex model of being cool-dry, warm-wet and cold-wet.