Prostaglandins and the lung

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1986 English Publisher:Springer Science and Business Media LLCJournal:Lung, volume 164, pages 65-77 (issn: 0341-2040, eissn: 1432-1750,

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Authors: S P, Hanley;

doi: 10.1007/bf02713630

pmid: 3084881

Prostaglandins and the lung

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Abstract

The series 2 prostaglandins and thromboxane A2 are synthesized by human lung tissue. When inhaled or infused, prostaglandins exert marked effects on both the airways and the pulmonary circulation. Increases in prostaglandin and thromboxane A2 synthesis occur in asthma, the adult respiratory distress syndrome, and pulmonary hypertension and are implicated as causes of these disorders. Inhibition of prostaglandin synthesis may improve or worsen asthma.

Related Organizations

University of Nottingham
United Kingdom
City Hospital
United Kingdom

Keywords

Heart Defects, Congenital, Respiratory Distress Syndrome, Arachidonic Acid, Prostaglandin Antagonists, Respiratory Tract Diseases, Smoking, Bronchi, Arachidonic Acids, In Vitro Techniques, Asthma, Mucus, Thromboxane A2, Prostaglandins, Animals, Humans, Pulmonary Embolism, Lung

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