The value of prostatic specific antigen density in the early diagnosis of prostate cancer

descriptionPublicationkeyboard_double_arrow_right Article 01 May 1998 Greece English Publisher:Springer Science and Business Media LLCJournal:International Urology and Nephrology, volume 30, pages 305-310 (issn: 0301-1623, eissn: 1573-2584,

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Authors: Deliveliotis, Ch.; Louras, G.; Kyriazis, P.; Gyftopoulos, A.; Louka, L.; Alargof, E.;

doi: 10.1007/bf02550314

pmid: 9696337

The value of prostatic specific antigen density in the early diagnosis of prostate cancer

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Abstract

In order to differentiate benign from malignant prostatic lesions, 42 patients were evaluated using the prostate specific antigen density (PSAD) test. All patients were evaluated with PSA determination, digital rectal examination (DRE), transrectal ultrasonography (TRUS) and ultrasound-guided prostatic biopsies. PSA was analyzed by the I-MX ABBOT assay. PSAD was determined by dividing the serum PSA by the volume of the prostate. Prostatic biopsies identified cancer in 3 of the 42 patients (6.38%). It is concluded that PSAD is valuable for the early diagnosis of localized prostatic carcinoma, especially when there are negative findings from DRE and/or TRUS.

Country

Greece

Related Organizations

Sismanoglio General Hospital
Greece
National and Kapodistrian University of Athens
Greece

Keywords

Male, Biopsy, Needle, Prostate, Prostatic Neoplasms, Middle Aged, Prostate-Specific Antigen, Predictive Value of Tests, Biomarkers, Tumor, Humans, Physical Examination, Aged, Ultrasonography

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