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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Lipidsarrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Lipids
Article . 1970 . Peer-reviewed
License: Wiley Online Library User Agreement
Data sources: Crossref
Lipids
Article . 1970
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Cholesterol metabolism and vitamin B6: II. Intestinal cholesterogenesis in vitamin B6 deficient rats

Authors: M D, Avery; P J, Lupien;

Cholesterol metabolism and vitamin B6: II. Intestinal cholesterogenesis in vitamin B6 deficient rats

Abstract

AbstractThe in vitro incorporation of 1‐14C‐acetate into cholesterol by vitamin B6 deficient and pair‐fed rat intestinal tissue was assayed. It was found that vitamin B6 deficiency increases, by a twofold factor, the incorporation of 1‐14C‐acetate into the cholesterol biosynthetic chain, when using a segment of the ileum, and on the other hand no increase was observed when using a segment from the jejunum. The production of14CO2 from 1‐14C‐acetate was not found altered by a vitamin B6 deficiency when using segments from the jejunum or the ileum. The effect of sodium cholate and sodium chenodeoxycholate on the incorporation of radioactivity into cholesterol and on the production of radioactive CO2, with 1‐14C‐acetate as a substrate, was assayed with the two groups of animals. The significance of these findings and the posible relationships between these factors are discussed.

Related Organizations
Keywords

Carbon Isotopes, Depression, Taurine, Acetates, Carbon Dioxide, Rats, Bile Acids and Salts, Cholesterol, Jejunum, Ileum, Intestine, Small, Animals, Humans, Vitamin B 6 Deficiency

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Average
Average
Average
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