A combinatorial data analysis strategy is reviewed that is designed to compare two arbitrary measures of proximity defined between the objects from some set. Based on a particular cross-product definition of correspondence between these two numerically specified notions of proximity (typically represented in the form of matrices), extensions are then pursued to indices of partial association that relate the observed pattern of correspondence between the first two proximity measures to a third. The attendant issues of index normalization and significance testing are discussed; the latter is approached through a simple randomization model implemented either through a Monte Carlo procedure or distributional approximations based on the first three moments. Applications of the original comparison strategy and its extensions to partial association may be developed for a variety of methodological and substantive tasks. Besides rank correlation, we emphasize the topics of spatial autocorrelation for one variable and spatial association between two and mention the connection to the usual randomization approach for one-way analysis-of-variance.