An epithermal energy neutron irradiation facility has been used to perform instrumental activation analysis for iodine, silicon, nickel, zirconium, uranium and thorium. The facility, which is adjacent to the fuel of the University of Virginia 2.0 MW pool reactor, consists of a dry sample region surrounded by a fixed cadmium shield. A boron nitride capsule can be used to hold the sample in the cadmium facility to further enhance the reduction of thermal neutron activation. The neutron fluence rate is 2.2×1016 n·m−2·s−1 for fission spectrum energy neutrons (measured with Ni(n,p)Co) and 8.2·1015 n·m−2·s−1 for resonance energy neutrons (measured with gold).