Silymarin, an inhibitor of prostaglandin synthetase

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1979 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 35, pages 1,550-1,552 (issn: 0014-4754, eissn: 1420-9071,

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Authors: F, Fiebrich; H, Koch;

doi: 10.1007/bf01953185

pmid: 118049

Silymarin, an inhibitor of prostaglandin synthetase

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Abstract

Silybin (I), silydianin (II) and silychristin (III), the main constituents of silymarin, inhibit the formation of prostaglandins in vitro. The inhibition is log-linearly dependent on the concentration of the effectors.

Related Organizations

University of Vienna
Austria

Keywords

Flavonoids, Male, Kinetics, Structure-Activity Relationship, Stomach, Animals, Cyclooxygenase Inhibitors, Rats, Silymarin

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