Strain differences in the pattern and intensity of wheel running activity in laboratory rats
Copyright policy )Strain differences in the pattern and intensity of wheel running activity in laboratory rats
Wheel running activity rhythms of three inbred rat strains, ACI/Ztm, BH/Ztm, and LEW/Ztm, were compared in order to evaluate the effect of genetic differences on circadian rhythm parameters. Significant strain differences were found in the general pattern of the activity rhythms and their characteristic periodicities as well as in the amount and duration of wheel running activity and the timing of activity onsets and offsets. The results suggest that genetic differences exist in the coupling of the multiple circadian oscillators that generate the overall pattern of wheel running activity.
- University of Stuttgart Germany
- University of Konstanz Germany
Activity Cycles, Male, Time Factors, Physical Exertion, 590, 610, Rats, Inbred Strains, Tagesrhythmus , Ratte, 630, Circadian Rhythm, Rats, Rats, Inbred ACI, Tagesrhythmus, Ratte, Species Specificity, Rats, Inbred Lew, Animals
Activity Cycles, Male, Time Factors, Physical Exertion, 590, 610, Rats, Inbred Strains, Tagesrhythmus , Ratte, 630, Circadian Rhythm, Rats, Rats, Inbred ACI, Tagesrhythmus, Ratte, Species Specificity, Rats, Inbred Lew, Animals
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