The solubility properties of granulopoiesis inhibiting factor

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1975 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 31, pages 1,357-1,359 (issn: 0014-4754, eissn: 1420-9071,

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Authors: W R, Paukovits; J B, Paukovits;

doi: 10.1007/bf01945825

pmid: 128468

The solubility properties of granulopoiesis inhibiting factor

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Abstract

The solubility of granulopoiesis inhibiting factor (GIF) in various aqueous and organic solvents was investigated. GIF is soluble in water, 10% acetic acid, and 10% pyridine. It is not extractable by 1-butanol at low and high pH. A high solubility was found in polar organic solvents (ethanol-acetone 9:1, and chloroform-methanol 1:1), whereas GIF seems to be insoluble in pure chloroform.

Related Organizations

University of Vienna
Austria
Universitätszahnklinik Wien
Austria

Keywords

Dose-Response Relationship, Drug, Bone Marrow Cells, In Vitro Techniques, Growth Inhibitors, Hematopoiesis, Rats, Solubility, Bone Marrow, Leukocytes, Solvents, Animals, Cells, Cultured, Granulocytes, Thymidine

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