The present investigation explores the relationship between adolescent autonomy and parental stress among families with children aged 10-17. Independent measures were obtained from parents and children. Parents of early adolescent children reported significantly more stress than parents of preadolescents or middle adolescents. Parents of first-born children reported significantly more stress than did more experienced parents. Although mothers and fathers reported comparable levels of overall parental stress, their stress was, in part, the result of different factors. Fathers reported higher levels of stress if their children reported not following their advice and being involved in deviant activities. For mothers, stress was significantly related to their children's desire for greater autonomy. Emotional detachment was not a significant predictor of parental stress for either mothers or fathers. Implications of the findings for the parent-child relationship during adolescence are discussed.